Quick Reviews of Nolvadex:
1. Nolvadex (Tamoxifen Citrate) is used as an anabolic steroid cycle for bodybuilding
2. Nolvadex also used for PCT cycle as a post anabolic steroid
3. Tamoxifen, an anticancer drug, is given to treat breast cancer in women and men.
4. Nolvadex is recommended to be stacked with highly aromatizable steroids like Dianabol and testosterone during steroid cycle or pct cycle.
CAS No: 54965-24-1
Melting Point: 140-144°C
Boiling point: 482.3°C at 760 mmHg
Einecs No: 234-118-0
Standard: Enterprise Standard
Storage: Shading, confined preservation
Usage: It’s used to anti-estrogen fertility inducer, the objects in dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecologic diseases;It is used as a first line defense against breast cancer.
Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4-hydroxytamoxifen. In other tissues such as theendometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist. Tamoxifen is the usual endocrine(anti-estrogen) therapy for hormone receptor-positive breast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting.
Some breast cancer cells require estrogen to grow. Estrogen binds to and activates the estrogen receptor in these cells. Tamoxifen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, tamoxifen acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. Hence breast cancer cell growth is blocked.
Tamoxifen was discovered by pharmaceutical company Imperial Chemical Industries(now AstraZeneca) and is sold under the trade names Nolvadex,Istubal, and Valodex. However, the drug has been widely referred to by its generic name "tamoxifen", even before its patent expiration.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Usage of Nolvadex