|Alias:||TH-9507, ThGRF(1-44), Hex-hGRF|
|Appearance:||White Lyophilized Powder|
|Method of Analysis:||HPLC|
How does it use?
Tesamorelin is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using tesamorelin at home, a health care provider will teach you how to use it. Be sure you understand how to use tesamorelin. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
Use the proper technique taught to you by your doctor. Inject deep under the skin, NOT into a vein or muscle.Be sure to rotate your injection site on the stomach area with each dose as directed. Do not inject tesamorelin into scar tissue, bruises, or the belly button.
Tesamorelin needs to be mixed before use. Follow how to mix as you were told by the doctor.Do not use tesamorelin if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
Tesamorelin has been shown to reduce lipodystrophy in HIV-infected individuals. Lipodystrophy is a condition that causes changes in placement of body fat, including wasting and fat accumulation, and changes in metabolism. Similar to Tesamorelin is Sermorelin, which may be taken with GHRP-6 is clinical trials, that also promotes production and possible fat loss. Individuals with lipodystrophy may develop excess fat most notably around the liver, stomach, and other abdominal organs (visceral body fat).
1. Tesamorelin is a synthetic peptide consisting of all 44 amino acids of hGRF with the addition of a trans-3-Hexenoic acid group.Tesamorelin (also known as Egrifta) is a synthetic form of growth-hormone-releasing hormone which is used in the treatment of HIV-associated lipodystrophy.tendon fibroblasts in a dose-dependent manner as revealed by transwell filter migration assay. BPC 157 also dose dependently accelerated the spreading of tendon fibroblasts on culture dishes.
2. The F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157-treated fibroblasts. The protein expression and activation of FAK and paxillin were determined by Western blot analysis, and the phosphorylation levels of both FAK and paxillin were dose dependently increased by BPC 157 while the total amounts of protein was unaltered. In conclusion, BPC 157 promotes the ex vivo outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration of tendon fibroblasts, which is likely mediated by the activation of the FAK-paxillin pathway.
How to Store :
Store vials of tesamorelin powder in the refrigerator, do not freeze.
Store the diluent at room temperature away from moisture, heat, and light.
Throw away any unused vials after the expiration date on the label has passe