Quick Detail:
Product name | Dapoxetine Hydrochloride |
Other name | (1s)-n,n-dimethyl-3-naphthalen-1-yloxy-1-phenyl-propan-1-amine hydrochloride;DAPOXETINE HCL;DAPOXETINE HYDROCHLORIDE CHEMISTRY PURE 98.5% HPLC ;Rimonabant 75000;(aS)-N,N-Dimethyl-a-[2-(1-naphthalenyloxy)ethyl]benzenemethanamine;LY-21044;((S)-(+)-N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride);(S)-(+)--N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine |
CAS register number | 129938-20-1 |
EINECS | ----------------- |
Molecular formula | C9H7ClN2O5 |
Molecular weight | 258.62 |
Molecular structure | ![]() |
Assay | 99% |
Appearance | white powder |
Usage | Dapoxetine (dapoxetine) as a new fast SSRI, a short half life, a selective 5 - HT reuptake inhibitor (SSRI), for the treatment of premature ejaculation and erectile dysfunction. Dapoxetine is a selective 5 - HT reuptake inhibitor (SSRI), such drugs widely used to treat depression and related affective disorders |
Standard | Enterprise standard/ ISO9001 |
Price | Negotiated |
Minimum order quantity | 10g |
Package: | Exquisite and can according to customers’ requirement |
Shipping leading time | Within 24 hours after receiving the payment |
Payment options | Western Union, MoneyGram, bank transfer, bitcoin |
Shipping |
1)Express delivery with DHL,EMS,Fedex,HKEMS,TNT,UPS(within 5-7days after payment) 2)By sea (large quantity ,it will take 30-45days) |
Description:
Dapoxetine (dapoxetine) as a new fast SSRI, a short half life, a selective 5 - HT reuptake inhibitor (SSRI), for the treatment of premature ejaculation and erectile dysfunction. Dapoxetine is a selective 5 - HT reuptake inhibitor (SSRI), such drugs widely used to treat depression and related affective disorders.
Dapoxetine, marketed as (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18-64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.
Treat male premature ejaculation and erectile dysfunction. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE.
Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.
Effect:
However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.
Specifications:
COA:
ITEMS | STANDARD | RESULTS |
Characteristics | White or almost white crystalline powder | White crystalline powder |
Melting point | 175.0~177.0ºC | 174.0~179.0ºC |
Specific rotatlon | +128°±3(C=1,CH3OH) | +128°±3(C=1,CH3OH) |
Loss on drying | ≤0.5% | 0.32% |
Heavy metals | 0ppm | 0ppm |
Relative substance | ≤0.1% Total impurity |
0.07% |
Assay(on drled basis) | ≥99.5% | 99.61% |
Conclusion | It complies to prescrlbed enterprise standard |