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1, 4-Butanediol BDO Bodybuilding Legal Steroids Pharmaceutical Powders CAS 110-63-4

1, 4-Butanediol BDO Bodybuilding Legal Steroids Pharmaceutical Powders CAS 110-63-4

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1, 4-Butanediol BDO Bodybuilding Legal Steroids Pharmaceutical Powders CAS 110-63-4

1, 4-Butanediol (BDO) Bodybuilding Legal Steroids Pharmaceutical Powders CAS 110-63-4


BDO Usage and Synthesis

1,4-Butanediol Usage And Synthesis
Chemical Properties 1,4-butanediol (1,4-BD) is a colorless, viscous liquid derived from butane by placement of alcohol groups at each end of its molecular chain and is one of four stable isomers of butanediol.the hydroxyl function of each end group of the Butanediol reacts with different mono- and bifunctional reagents: for example with dicarboxylic acids to polyesters, with diisocyanates to polyurethanes, or with phosgene to polycarbonates. 1.4-Butanediol (BDO) is a high-quality intermediate. BDO and its derivatives are widely used for producing plastics, solvents, electronic chemicals and elastic fibers. Additionally BDO is also a building block for the synthesis of polyesterpolyols and polyetherpolyols. BASF is the most significant producer of 1,4-Butanediol and its derivatives worldwide.

00001. Butanediol and its derivatives is used in a broad spectrum of applications in the chemical industry; amongst others in the manufacturing of technical plastics, polyurethanes, solvents, electronic chemicals and elastic fibres.

00002. 1,4-Butanediol is used in the synthesis of epothilones, a new class of cancer drugs. Also used in the stereoselective synthesis of (-)-Brevisamide.

00003. 1,4-Butanediol's largest use is within tetrahydrofuran (THF) production, used to make polytetramethylene ether glycol, which goes mainly into spandex fibers, urethane elastomers, and copolyester ethers.

00004. It is commonly used as a solvent in the chemical industry to manufacture gamma-butyrolactone and elastic fibers like spandex.

00005. It is used as a cross-linking agent for thermoplastic urethanes, polyester plasticizers, paints and coatings.

00006. It undergoes dehydration in the presence of phosphoric acid yielded teterahydrofuran, which is an important solvent used for various applications.

00007. It acts an intermediate and is used to manufacture polytetramethylene ether glycol (PTMEG), polybutylene terephthalate (PBT) and polyurethane (PU).

00008. It finds application as an industrial cleaner and a glue remover.

00009. 1,4-butanediol is also used as a plasticiser (e.g. in polyesters and cellulosics), as a carrier solvent in printing ink, a cleaning agent, an adhesive (in leather, plastics, polyester laminates and polyurethane footwear), in agricultural and veterinary chemicals and in coatings (in paints, varnishes and films).

Uses butylene glycol is a solvent with good antimicrobial action. It enhances the preservative activity of parabens. Butylene glycol also serves as a humectant and viscosity controller, and to mask odor.
Uses 1,4-Butanediol is used to produce polybutyleneterephthalate, a thermoplastic polyester;and in making tetrahydrofuran, butyrolactones,and polymeric plasticizers.
Production Methods Methods of manufacturing:
The most prevalent 1,4-BD production route worldwide is BASF's Reppe process, which reacts acetylene and formaldehyde. Acetylene reacts with two equivalents of formaldehyde to form 1,4-butynediol, also known as but-2-yne- 1,4-diol. Hydrogenation of 1,4-butynediol gives 1,4-butanediol. 1,4-BD is also made on a large industrial scale by continuous hydrogenation of the 2-butyne- 1,4-diol over modified nickel catalysts. The one-stage flow process is carried out at 80 - 160 deg C and 300 bar.
Mitsubishi uses a three-step process:
(1) the catalytic reaction of butadiene and acetic acid yields 1,4-diacetoxy-2-butene;
(2) subsequent hydrogenation gives 1,4-diacetoxybutane; and
(3) hydrolysis leads to 1,4-butanediol.
General Description Odorless colorless liquid or solid (depending upon temperature).
Air & Water Reactions Highly flammable. 1,4-Butanediol is hygroscopic. Water soluble.
Reactivity Profile 1,4-Butanediol is heat and light sensitive. 1,4-Butanediol reacts with acid chlorides, acid anhydrides and chloroformates; reacts with oxidizing agents and reducing agents. 1,4-Butanediol is incompatible with isocyanates and acids; also incompatible with peroxides, perchloric acid, sulfuric acid, hypochlorous acid, nitric acid, caustics, acetaldehyde, nitrogen peroxide and chlorine.
Hazard Toxic by ingestion.
Health Hazard The acute toxic effects are mild. 1,4-Butanediolis less toxic than its unsaturate analogs,butenediol and the butynediol. The oralLD50 value in white rats and guinea pigsis ~2 mL/kg. The toxic symptoms fromingestion may include excitement, depressionof the central nervous system, nausea, anddrowsiness.
Health Hazard Ingestion of large amounts needed to produce any symptoms.
Fire Hazard Nonflammable liquid, flash point (open cup) 121°C.
Safety Profile A human poison by an unspecified route. Moderately toxic byingestion and intraperitoneal routes. Human systemic effects: altered sleep time. Combustible when exposed to heat or flame. To fight fire, use alcohol foam, mist, foam, CO2, dry chemical. Incompatible with oxidizing materials. When heated to decomposition it emits acrid smoke and fumes.
Purification Methods Distil the glycol and store it over Linde type 4A molecular sieves, or crystallise it twice from anhydrous diethyl ether/acetone, and redistil it. It has been recrystallised from the melt and doubly distilled in vacuo in the presence of Na2SO4. [Beilstein 1 IV 2515.]


BDO Quick Detail:

Product Name:1,4-Butanediol
MW: 90.12
Assay :99%
Grade: Pharmaceutical Grade
Appearance: Colorless Liquid
Delivery Time:3-7days after payment



It's an important raw materials of organic chemical and fine chemical, it is basic material in the production of polyethylene terephthalate (PBT) and PBT fiber plastic.

It's the main raw material to produce tetrahydrofuran (THF).


It's the main raw material to produce, and is mainly used for production of α -pyrrolidone and N-methyl pyrrolidone (NMP), and thus derived from vinyl pyrrolidone, polyvinylpyrrolidone and a series of high value-added products, widely used in pesticides, pharmaceuticals and cosmetics and other industries.



  • 1.1,4 butanediol is an important raw materials for organic and refined. It is the basic material for producing PBT plastics and fiber, and PBT is one of the five most promising engineering plastics.
  • 2. 1,4butanediol is the main raw material for producing THF, which is an important organic solvent. The polymeric compound PTMEG of THF forms the basic material for highly-elastic urethane elastic fiber, which is mainly used for producing high-grade sports wear and swimming suit that requir high elasticity.
  • 3. 1,4-butanediol is the main material for producing γ-butyrolacton, which is widely used in pesticide, pharmaceuticals, cosmetics and other industries due to its ability to produce 2-pyrrolidone, NMP and their derivatives NVP and PVP etc. high add-ons products.
  • 4. 1,4butanediol is the main material for producing polyurethane artificial leather, polyurethane, elastomer and polyurethane sole glue. polyurethane elastomer are widely used to manufacture elastic sole, auto solid fire, friction conveying belt and etc.

1, 4-Butanediol BDO Bodybuilding Legal Steroids Pharmaceutical Powders CAS 110-63-4 0