10-20 mg per day is a sufficient dose. It is recommended to start at 10mg per day to take advantage of the host’s sensitivity to the new chemical. 10 mg a day is aimed for endurance, and the higher the dosage the greater the fat loss benefits are going to be
Lab mice should be given dosages 45 minutes- 1 hour before exercise.
GW501516 has been tested for a 2 year study and has found no decreases or stagnation in effects. Most individuals run cycles for 12-14 weeks at a time with a 4-6 week break. This is normally to coincide with a SARM cycle, but there is no evidence showing that GW 501516 needs to be off-cycled after such a short amount of time. GW501516 was created for LONG TERM usage, so there is no reason why it shouldn’t be used that way.
Half life is between 16-24 hours and should be take at 10mg once a day or 10mg once every 10-12 hours if taken at a higher dose.
No PCT is needed, GW is recommended in combination with PCT if highly toxic anabolics have been used.
Highly recommended to use with a ketogenic diet.
Can be used in conjunction with anabolics and stimulants of any kind without adverse reactions
GW501516 (also known as GW-501,516, GW1516, GSK-516 and Endurobol)is a PPARδ receptor.It activates the same pathways activated through exercise, including PPARδ and AMP-activated protein kinase.It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease.GW501516 has a synergistic effect when combined with AICAR:The combination has been shown to significantly increase exercise endurance in animal studies more than either compound alone.
GW-501516 (GW-1516 or GSK-516) is a drug that acts as a PPAR modulator. GW-501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. It has been proposed as a potential treatment for obesity and related conditions, especially when used in conjunction with a synergistic compound AICAR, as the combination has been shown to significantly increase exercise endurance in animal studies.
A PPAR modulator allows the body to use more glucose and to create additional muscle tissue. One of the PPARs is GW-501516. It may be referred to as GW1516 or GSK-516 as well. It can help to reduce and even reverse various problems in men who are obese or that have symptoms of pre-diabetes due to problems with their metabolism. The use of GW-501516 may be a viable treatment for reducing obesity and various conditions that are linked to it.