Product name: Levothyroxine sodium
Key Words:Levothyroxine sodium,Levothyroxine sodium T4,Levothyroxine sodium,T4 Steroid hormone Powder,
1. CAS: 55-03-8
2. M. F: C15H20I4NNaO9
3. M. W: 888.93
4. Assay: 99%min
5. Standrad: USP29
6. Appearance: Gray to white powder
7. Function: Hormones and Regulation of Endocrine Function of Drug
8. Levothyroxine is a synthetic (man-made) version of the principle thyroid hormone, thyroxine (T4) that is made and released by the thyroid gland. Thyroid hormone increases the metabolic rate of cells of all tissues in the body. In the fetus and newborn, thyroid hormone is important for the growth and development of all tissues including bones and the brain. In adults, thyroid hormone helps to maintain brain function, food metabolism, and body temperature, among other effects
9. Also T3, Dmaa, Melanotan 1, Melanotan 2, etc
4/L-Thyroxine is pro-hormone, which your body converts into T3 at necessary rate only and thus it could be considered as much milder and safer drug than T3.
L-Thyroxine is an excellent fat burner since your metabolism is greatly increased while being on it. You can afford to be a little sloppier on pre-contest dieting since it will still burn fat when you are taking in a lot of calories since your metabolism is going haywire.
L-Thyroxine is widely used by bodybuilders and fitness addicts on pre-competition cycle in order to get relief, also used by overweighed people to reduce weight. It increases metabolism and produces general stimulating effects. However, this substance should be used wisely.
|Appearance||An odorless, almost white or buff colored powder||pass|
|Solubility||1,Very slightly soluble in water||pass|
|2,slightly soluble in alcohol||pass|
|3,practically insoluble in most other organic solvents||pass|
|4,disolves in diluted aqueous sodium hydroxide solutions||Pass|
|Identification||a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved.||pass|
|b)The retention time of the major peak is confirm to the RS||pass|
|Loss on Drying||Not more than 4.0%||0.46%|
C=1 in 1M HCl/EtOH 1:4
|+18 ~ +22o||+20.9o|
|Assay(HPLC)||Not less than 95.0%||99.18%|
|Levothyroxinesodium||Not more than 5.0%||0.68%|
Up to the Standard for Export
➣ Hypothyroidism; treatment or prevention of euthyroid goiter
Adults: For healthy adults younger than age 50 and those over age 50 who have recently been treated or undergoneshort-term therapy, start at full replacement dosage of 1.7 mcg/kg P.O. daily, given 30 minutes to 1 hour before breakfast.For patients older than age 50 or younger than age 50 with heart disease, 25 to 50 mcg P.O. daily, increased q 4 to 6weeks. In severe hypothyroidism, initial dosage is 12.5 to 25 mcg P.O. daily, adjusted by 25 mcg daily q 2 to 4 weeks.For patients who can't tolerate oral doses, adjust I.M. or I.V. dosage to roughly half of oral dosage.
➣ Congenital hypothyroidism
Children older than age 12 who have completed puberty and growth: 1.7 mcg/kg P.O. daily
Children older than age 12 who have not completed puberty and growth: Up to 150 mcg or 2 to 3 mcg/kg P.O.daily
Children ages 6 to 12: 4 to 5 mcg/kg P.O. daily
Children ages 1 to 5: 5 to 6 mcg/kg P.O. daily
Infants ages 6 to 12 months: 6 to 8 mcg/kg P.O. daily
out of reach of children.
Keep this medication in the container and tightly closed,
Store it at room temperature and away from excess heat and moisture .
Throw away any medication that is outdated or no longer needed.
Talk to your doctor about the proper disposal of your medication.