Product Name: Lorcaserin Hcl
English name: Lorcaserin hydrochloride
English Synonyms: (1R) -8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine hydrochloride; APD 356; APD-356; UNII-0QJF08GDPE; Lorcaserin HCl; (R) – 1H-3-Benzazepine, 8-Chloro-2,3,4,5-Tetrahydro-1-Methyl-, Hydrochloride
CAS: 846589-98-8
Formula: C11H14ClN · ClH
MW: 232.1525
Molecular Structure:
Assay:96.21%
Appearance:white powder
Boiling point : 288.125°C at 760 mmHg
Flash point : 128.054°C
Product usage : Medicine reducing weight and antidepressants
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Lorcaserin HCl is an FDA-approved prescription weight-loss medication that, when used with diet and exercise, can help some overweight adults with a weight-related medical problem, or obese adults, lose weight and keep it off.
Lorcaserin HCl a serotonin 2C receptor agonist. It hasbeen shown to decrease food consumption and promote SA tiety by selectivelyactivating serotonin 2C receptors in the brain.
Lorcaserin HCl is specifically indicated as an adjunct to a reduced-calorie diet andincreased physical activity for chronic weight management in clinically obeseadults (BMI of 30 kg/m2 or greater) and overweight adults (BMI of 27 kg/m2 orgreater) with at least one weight-related comorbid condition.
Lorcaserin HCl is supplied as a tablet designed for oral administration. The recommendeddose is one 10mg tablet twice daily. Use of Lorcaserin HCl should be discontinued if 5%weight loss is not achieved by week 12 of treatment.
Items | Standard | Results |
Description | White to kind of white powder | kind of white powder |
Melting point | 193.0-200 | 196.0-198.9 |
Water | 5-6.5% | 5.6% |
Solubility | Soluble in methanol | Complies |
PH | 4.0-6.0 | 5 |
Heavy Metals | <10ppm | Complies |
Assay | >96% | 96.21% |
Residue on ignition | <0.1% | 0.03% |
Single impurity | <0.2% | 0.19% |
Conclusion | Up to the Standard USP 32. |
Lorcaserin is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in obese adults (a BMI of 30 kg/m2 or greater) or in overweight patients (BMI of 27 kg/m2 or greater) with at least one weight-related comorbid condition, such as hypertension, type-2 diabetes, or dyslipidemia.
The recommended dose is 10 mg orally twice daily with or without food. If you do not lose a certain amount of weight during the first 12 weeks of your treatment, it is not likely that you will benefit from taking lorcaserin. Your doctor may tell you to stop taking lorcaserin if you do not lose enough weight during the first 12 weeks of your treatment.