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|Product name:||Tamoxifen Citrate||Other Name:||Nolvadex;TAM|
|Molecular formula:||C26H29NO||Molecular weight:||371.51|
|Appearance:||White Powder||Standard:||Enterprise Standard/ ISO9001|
|Usage:||Hormones And Regulation Of Endocrine Function Of Drug||Type:||Anti Estrogen Steroids|
Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, 4-hydroxytamoxifen. In other tissues such as theendometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist. Tamoxifen is the usual endocrine(anti-estrogen) therapy for hormone receptor-positive breast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting.
Some breast cancer cells require estrogen to grow. Estrogen binds to and activates the estrogen receptor in these cells. Tamoxifen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, tamoxifen acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. Hence breast cancer cell growth is blocked.
Nolvadex Post Cycle Doses:
For a good Nolvadex post cycle plan very few will ever need more than 40mg per day and most will find that ending with a lower dose of 20mg per day to be just about perfect. For the healthy adult male a good Nolvadex post cycle plan will run for approximately 4-6 weeks in total duration; 4 weeks should be the standard with 1-2 additional weeks being added if necessary. In most cases the additional weeks will only be needed if the anabolic steroid cycle was strong, was extended and of a high suppressive nature. A solid Nolvadex post cycle plan for most any man to follow would look something like this:
HCG & Nolvadex Post Cycle Plans:
Many performance enhancers often experience a higher rate of recovery with the addition of Human Chorionic Gonadotropin (hCG) alongside their Nolvadex post cycle plan. Such an addition is not always necessary but it can be quite beneficial and most any anabolic steroid cycle that extends 16 weeks or more, that is comprised of very suppressive steroids or a combination of both will warrant solid hCG therapy. For those who follow an hCG and Nolvadex post cycle plan the hCG will be used first; a good plan will consist of ten days of hCG use prior to Nolvadex therapy and will generally fall in the range of 1,000iu per day every day for ten days; Nolvadex therapy beginning the day after the last hCG administration.
Implementing Nolvadex Post Cycle Therapy:
We do not simply and arbitrarily end our cycle of anabolic steroids and start our post cycle recovery; you must have an understanding of the steroids you were using in order to determine timing and this is very important. If you begin your Nolvadex post cycle plan too soon and you still have a lot of suppressive anabolic steroids in your system the whole recovery process will be a waste.
If your cycle ends with short ester anabolic steroids you may start your recovery process 2-3 days after your last injection; whether you are going to include hCG or not you will still start 2-3 days after the anabolic steroid cycle ends. If however your cycle ends with any long ester based steroids things will change; in this instance if you are going to include hCG into your Nolvadex post cycle plan you will begin hCG use ten days after your last steroidal injection; if your cycle ended with very long ester gear such as Deca-Durabolin it might be wise to wait a full two weeks. If your cycle ends with long ester steroids and you are not including hCG you will need to wait 2 weeks before Nolvadex post cycle therapy begins with 3 weeks being optimal if steroids such as Deca-Durabolin were being used at the end of the cycle.