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|Other Name:||L-Triiodothyronine; Cytomel T3||Molecular formula:||C15H11I3NNaO|
|Molecular weight:||672.96||Appearance:||White Or Light Yellow Powder, Almost Tasteless.|
|Type:||Weight Loss Steroids||Market:||Global|
Why choose T3 as weight loss product?
When T3 increases the rate of metabolism, it does the following:
* Increase the amount of oxygen and energy used up by the body
* Increase the amount of calories required for normal body processes even when the muscles are rested
* Increase the population of sodium/potassium/ATPase, the primary energy-generating complex in the body
* Increase the use and breakdown of many nutrient macromolecules produced in the body
Brife Info about L-Triiodothyronine(T3)
As a thyroid hormone, T3, affects almost every physiological process in the body, including growth and development,metabolism, body temperature, and heart rate.
T3, regulates cellular growth rate, growth hormone production, the levels of nuclear T3 receptors via distinct dose response ranges in cultured GC cells.
Evidence for mediation by the nuclear T3 receptor, (T3) stimulates growth of cultured GC cells by action early in the G1 period.
Evidence for Cellular Binding Proteins and Conversion of T4 to T3, metabolism of L-Thyroxine (T4) and L-Triiodothyronine (T3) by Human Fibroblasts in Tissue Culture.
T3 VS T4
T4 is deiodinated by three deiodinase enzymes to produce the more-active triiodothyronine.T3 is the more metabolically active hormone produced from T4.
Deiodinase enzyme one accounts for 80% of the deiodination of T4, present in liver, kidney, thyroid, and (to a lesser extent) pituitary.
Deiodinase enzyme two presents in CNS, pituitary, mediates negative feedback on thyroid-stimulating hormone, also presents in brown adipose tissue, and heart vessel, which is predominantly intracellular.
Deiodinase enzyme three, converts T4 into reverse T3, which, unlike T3, is inactive, it present in placenta, CNS, and hemangioma.
T3 may increase serotonin in the brain, in particular in the cerebral cortex, and down-regulate 5HT-2 receptors.
T3 stimulates the breakdown of cholesterol and increases the number of LDL receptors, increases the rate of lipolysis.
T3 potentiates the effects of the β-adrenergic receptors on the metabolism of glucose, increases the rate of glycogen breakdown and glucose synthesis ingluconeogenesis.
T3 affects the lungs and influences the postnatal growth of the central nervous system, stimulates the production of myelin, the production of neurotransmitters, and the growth of axons, also important in the linear growth of bones, has profound effect upon the developing embryo and infants.
T3 stimulates the production of RNA Polymerase, increases the rate of protein synthesis and protein degradation, and the rate of protein degradation exceeds the rate of protein synthesis in excess, then the body may go into negative ion balance.
The basal metabolic rate is the minimal caloric requirement needed to sustain life in a resting individual. T3 increases the basal metabolic rate and, thus, increases the body's oxygen and energy consumption.
With a few exceptions including the spleen and testis, T3 acts on the majority of tissues within the body. It increases the production of the Na+/K+ -ATPase without disrupting transmembrane ion balance, and increases the turnover of different endogenous macromolecules by increasing their synthesis and degradation generally.
T3 increases the heart rate and force of contraction, then increases cardiac output by increasing β-adrenergic receptor levels in myocardium, and results in increased systolic blood pressure and decreased diastolic blood pressure. The latter two effects act to produce the typical bounding pulse seen in hyperthyroidism, also upregulates the thick filament protein myosin, which helps to increase contractility.